Borys, Agnieszka M.Jonas, KamilSochacka, EwelinaKołton-Wróż, MariaWołkow, PawełWypasek, EwaPelc, EwaMałecki, Maciej T.Kopeć, GrzegorzTotoń-Żurańska, Justyna2026-06-242026-06-242025-08-11Kardiologia Polska. Polish Heart Journal 2026, Vol. 84, No 20022-9032https://hdl.handle.net/11315/31601Introduction: "Pulmonary arterial hypertension (PAH) is a rare vascular disorder characterized by structural changes in the pulmonary vessels and elevated pressure in the pulmonary artery, leading to right ventricular hypertrophy and right heart failure [1–3]. Idiopathic PAH (IPAH) is diagnosed by excluding other potential causes of pulmonary hypertension. The most commonly mutated gene in PAH codes the bone morphogenic protein receptor 2 (BMPR2), a transmembrane receptor involved in cell-specific BMP signaling [4, 5]. In this study, we present the first comprehensive analysis of BMPR2 gene alterations in Polish patients diagnosed with IPAH." (...)enCreative Commons Attribution International (CC BY) licensegenetic alterationsbone morphogenic protein receptor 2idiopathic pulmonary arterial hypertensionMedycynaZdrowieArtykuł1897-427910.33963/v.phj.108053