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Pozycja Biochemical and mineral profile of various parts of fruits Styrian oil squash (Cucurbita pepo styriaca group) determined during ripening phases(De Gruyter, 2026-05-13) Bella, Vladimíra; Fatrcová Šramková, Katarína; Vergun, Olena; Grygorieva, Olga; Brindza, Ján; Nowicki, Marcin; Ivanišová, Eva; Kowalczewski, Przemysław ŁukaszAbstract: "The natural mutant Cucurbita pepo Styriaca Group originates from Styria (Austria), known for its hull-less seeds and dark green pumpkin oil with a roasted nut flavour. Seeds and fruit tissues, such as mesocarp, endocarp, exocarp are notable for their nutritional and bioactive compounds, with potential applications in nutraceuticals and pharmaceuticals. Our research focused on these components throughout five distinct ripening stages over two consecutive years 2020–2021, examining the dynamics of proteins, amino acids, lipids, minerals, and heavy metals. Protein content varied significantly, the highest in the mesocarp and the lowest in the seeds. Glutamic acid and aspartic acid dominated the amino acid profile, while essential amino acids were most abundant in seeds, with leucine, lysine, phenylalanine, valine, and isoleucine reaching notable concentrations. Mineral composition shifted during maturation: potassium and phosphorus declined, calcium increased, and elements such as magnesium, copper, and zinc rose in later stages. Heavy metals remained within safe limits across all phases. Biochemical and mineral profiles vary significantly between tissue types and between maturation stages. Our findings highlight young, unripe fruits as a valuable source of proteins and lipids, with the largely neglected endocarp emerging as a promising raw material for diverse applications. Harnessing these underutilized components could open new avenues in the agri-food sector, animal nutrition, and the pharmaceutical and cosmetic industries, aligning with global trends and local opportunities."(...)Pozycja Interdyscyplinarne aspekty nauk o zdrowiu(Oficyna Wydawnicza AFM, 2010) Goździalska, Anna; Jaśkiewicz, Jerzy; Lizak, Dorota; Kalemba-Drożdż, Małgorzata; Drąg, Jagoda; Gawędzka, Anna; Brzewski, Paweł; Wojas-Pelc, Anna; Limanówka, Danuta; Foryś, Zofia; Pach, Dorota; Targosz, Dorota; Gołkowski, Filip; Dęsoł, Agnieszka; Abramczyk, Anna; Seń, Mariola; Felińczak, Anna; Dębska, Grażyna; Hama, Faustina; Krzyżanowski, Dominik; Słobodzian, Anna; Knapik-Czajka, Małgorzata; Kozak, Lidia; Drożdż, Włodzimierz; Kurleto-Kalitowska, Ewa; Romanowska, Urszula; Lipińska, Maria; Maj, Krystyna; Lampart, Beata; Laskowska, Justyna; Drożdż, Włodzimierz; Kadučáková, Helena; Lehotská, Mária; Czajkowski, Wojciech; Pawłowski, Leszek; Kiwnik-Dahm, Aneta; Cepuch, Grażyna; Futoma, Bernadetta; Pasek, Małgorzata; Jackowska, Renata; Dębska, Grażyna; Jaśkiewicz, JerzyPozycja Nowe wskaźniki w patomechanizmie rozwoju otyłości – elongazy i desaturazy nienasyconych kwasów tłuszczowych(Oficyna Wydawnicza AFM, 2010) Drąg, Jagoda; Goździalska, Anna; Gawędzka, Anna; Jaśkiewicz, JerzyObesity is a disease caused by a disorder of energy homeostasis and is manifested as an excessive accumulation of fat. Almost all cases of obesity result from a combination of genetic predisposition and a chronic imbalance between energy intake, energy utilization for basic metabolic processes, and energy expenditure from physical activity. Obesity is a risk factor for major causes of death, including cardiovascular disease, numerous cancers, and diabetes, and is linked with markedly diminished life expectancy. Complication of obesity include metabolic syndrome. The metabolic syndrome is characterized by a group of metabolic risk factors such as abdominal obesity (excessive fat tissue in and around the abdomen), atherogenic dyslipidemia (high triglycerides, low HDL cholesterol and high LDL cholesterol) and elevated blood pressure. The incidence of obesity has increased substantially in recent years and constantly growing number of obese patients necessitates the development of high requirements to reduce the impact of adverse health effects associated with metabolic syndrome. It is important therefore to examine the influence of nutrients, particularly fatiy acids, in the development of obesity and metabolic syndrome. The aim of our study was determine the influence of the high-carbohydrate diet on hepatic gene expression for Elovl 2, Elovl 5, Δ5 desaturase, Δ6 desaturase, Scd1 and Scd2. We demonstrated that mRNA expression level of Elovl 5, Δ5 desaturase, Δ6 desaturase and Scd2 in liver of rats fed high-carbohydrate diet was similar to the levels of mRNA for the same enzymes in liver of animals fed standard diet. Statistically significant differences in the levels of mRNA expression was demonstrated for elongases 2 and SCD1 (Δ9 desaturase-isoform 1).