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Antioxidant and Antiproliferative Activities of a Nonprotein Potato Juice Fraction Against Gastrointestinal Cancer cells: A Preliminary Study
(Oficyna Wydawnicza AFM Uniwersytetu Andrzeja Frycza Modrzewskiego w Krakowie, 2026-06-18) Kowalczewski, Przemysław Łukasz; Olejnik, Anna; Rybicka, Iga; Białas, Wojciech; Kornak-Kulka, Paulina; Lewandowicz, Grażyna
Abstract: "Research results that have appeared in recent years indicate the broad biological activity of potato juice (PJ). The activities that are described include anti-inflammatory, antioxidant and cytotoxic effects. This paper is a report on the antiproliferative and antioxidant activity of the nonprotein fraction (NPF) of PJ. NPF was obtained using a novel method of enzymatic protein hydrolysis combined with multistage membrane separation, characterized chemically and compared with raw PJ. Antioxidant as well as antiproliferative activities against human cancer cells isolated from the colon (Caco-2 and HT-29 cell lines), and normal cells isolated from the human normal colon (CCD 841 CoN cell line) were investigated. NPF was shown to have a higher antiproliferative activity than PJ, and it was more effective in cancer than in normal cells."(...)