Success Rates of Assisted Reproduction in Couples with Poor Ovarian Response and Oligospermia

dc.contributor.authorWyroba, Jakub
dc.contributor.authorKochan, Joanna
dc.contributor.authorBrązert, Maciej
dc.contributor.authorKordowitzki, Paweł
dc.date.accessioned2026-09-11T13:33:45Z
dc.date.available2026-09-11T13:33:45Z
dc.date.issued2025-09-24
dc.description.abstractAbstract: „Recent progress in assisted reproductive medicine has introduced novel therapeutic possibilities for couples experiencing various reproductive challenges or subfertility. A critical concern in this field is the diminished ovarian response to hormonal treatments preceding ovum pickup, necessitating personalised and optimised protocols to enhance ovarian response across different age groups. Furthermore, a common male factor in IVF couples, oligozoospermia, characterised by a low sperm count, significantly impacts the success rates of assisted reproductive technologies, posing an increasing challenge for in vitro fertilisation clinics. Lifestyle choices, dietary habits, and overall health behaviours have also demonstrably affected fertility outcomes in the 21st century. This original article aims to highlight the synergistic importance of both partners’ health, specifically addressing poor ovarian response and oligozoospermia, in achieving successful conception. Our study analysed intracytoplasmic sperm injection outcomes in couples affected by both aforementioned conditions and proposed an optimal management strategy. This study shows that oligozoospermia significantly reduced ICSI fertilisation and cleavage rates. Poor ovarian responders experienced more cancelled cycles due to fewer embryos. While blastocyst rates relative to zygotes were comparable, overall success was lower in groups with male factor infertility and poor ovarian response, necessitating personalised treatment approaches.”(…)
dc.identifier.citationCells 2025, Vol. 14, Issue 19
dc.identifier.doihttps://doi.org/10.3390/cells14191492
dc.identifier.issn2073-4409
dc.identifier.urihttps://hdl.handle.net/11315/31619
dc.language.isoen
dc.publisherMDPI
dc.rightsCC BY 4.0
dc.subjectpoor ovarian response
dc.subjectin vitro fertilization
dc.subjectoligospermia
dc.subjectwomen
dc.subjectmen
dc.subject.otherMedycyna
dc.subject.otherZdrowie
dc.titleSuccess Rates of Assisted Reproduction in Couples with Poor Ovarian Response and Oligospermia
dc.typeArtykuł
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