Genetic alterations in bone morphogenic protein receptor 2 in Polish patients diagnosed with idiopathic pulmonary arterial hypertension

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dc.contributor.authorBorys, Agnieszka M.
dc.contributor.authorJonas, Kamil
dc.contributor.authorSochacka, Ewelina
dc.contributor.authorKołton-Wróż, Maria
dc.contributor.authorWołkow, Paweł
dc.contributor.authorWypasek, Ewa
dc.contributor.authorPelc, Ewa
dc.contributor.authorMałecki, Maciej T.
dc.contributor.authorKopeć, Grzegorz
dc.contributor.authorTotoń-Żurańska, Justyna
dc.date.accessioned2026-06-24T07:10:28Z
dc.date.available2026-06-24T07:10:28Z
dc.date.issued2025-08-11
dc.description.abstractIntroduction: "Pulmonary arterial hypertension (PAH) is a rare vascular disorder characterized by structural changes in the pulmonary vessels and elevated pressure in the pulmonary artery, leading to right ventricular hypertrophy and right heart failure [1–3]. Idiopathic PAH (IPAH) is diagnosed by excluding other potential causes of pulmonary hypertension. The most commonly mutated gene in PAH codes the bone morphogenic protein receptor 2 (BMPR2), a transmembrane receptor involved in cell-specific BMP signaling [4, 5]. In this study, we present the first comprehensive analysis of BMPR2 gene alterations in Polish patients diagnosed with IPAH." (...)
dc.identifier.citationKardiologia Polska. Polish Heart Journal 2026, Vol. 84, No 2
dc.identifier.doi10.33963/v.phj.108053
dc.identifier.eissn1897-4279
dc.identifier.issn0022-9032
dc.identifier.urihttps://hdl.handle.net/11315/31601
dc.language.isoen
dc.publisherVia Medica
dc.rightsCreative Commons Attribution International (CC BY) license
dc.subjectgenetic alterations
dc.subjectbone morphogenic protein receptor 2
dc.subjectidiopathic pulmonary arterial hypertension
dc.subject.otherMedycyna
dc.subject.otherZdrowie
dc.titleGenetic alterations in bone morphogenic protein receptor 2 in Polish patients diagnosed with idiopathic pulmonary arterial hypertension
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