Pituitary tumours are slow-growing benign neoplasms that account for approximately 15% of all intracranial tumours. The diagnosis of pituitary tumours includes clinical signs and neuroimaging studies. This case report concerns a woman, now 71 years old, who was first hospitalised for increasing headaches and vomiting at the age of 38. A diagnosis of meningeal syndrome and destruction of the saddle of Turkey was made. The first operation to remove the pituitary macroadenoma via the transsphenoidal route took place fifteen years after diagnosis and, due to regrowth of the inactive pituitary adenoma, reoperation was performed twice after a further five years. The last surgery was complicated by paralysis of the right peroneal nerve and paralysis of the adductor nerve on the left side. The implementation of nursing care is based on the application of measures aimed at reducing discomfort, eliminating possible complications, increasing the patient’s level of independence, providing education and counselling on lifestyle changes, and coping with the limitations imposed by the disease.