Responsible business is created based on pursuit of common values, including those that are characteristic of the integrating Europe. Integration is affected by cultural diversity of individual countries. It translates into organisational cultures of the individual business entities that are functioning in the European market. In particular, the organisational culture is important in the corporations functioning in the global market, and executing processes of internationalisation of their activities. The concept that takes into account common values irrespective of the place of executing business activities is CSR (corporate social responsibility). CSR refers to simultaneous pursuit of social, ecological and economic objectives. The premises of CSR have been adopted by the international community. In the European Union market, this concept may be conducive to integration processes through the execution of common European values by companies, based on the expectations of their shareholders. The paper analyses the effect of cultures of European countries as well as the effect of governments of particular countries on management in companies and local conditions on the execution of CSR. Execution of CSR, as well as taking into consideration the sustainability premises, may constitute the basis for creation of responsible business.