1.2 Artykuły z wydawnictw zewnętrznych

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Anti-inflammatory properties of cantharellus cibarius from in vitro culture enriched in zinc
(Polish Pharmaceutical Society, 2018) Gudula-Argasińska, Joanna; Grzywacz, Agata; Krakowska, Agata; Opoka, Włodzimierz; Muszyńska, Bożena
Cantharellus cibarius Fr. (Basidiomycota), commonly known as Chanterelle, is one of the most valued and currently most often collected species of edible mushrooms in Europe, Asia, Africa, and the northern USA. Cantharellus genus (chanterelles) includes seventy species, seven of which are noted in Europe. Due to the valuable and biologically active metabolite content in the fruiting bodies, C. cibarius was selected for the study. The combinations of carbohydrates, amino acids, unsaturated fatty acids, and vitamins revealed the nutritional, in particular, anti-inflammatory properties of this species. Zinc (Zn) is one of the microelements present in significant quantities in the fruiting bodies and biomass from in vitro cultures of edible mushrooms. Zn plays a crucial role as an anti-inflammatory agent. This paper presents a study on investigation of the pro- or antiinflammatory properties of mushroom extracts from fruiting bodies and biomass from in vitro culture of C. cibarius enriched in Zn. As an additive to the modified Oddoux liquid medium, on which in vitro C. cibarius cultures were grown, the following two compounds were used: zinc sulfate and zinc hydroxyaspartate. In order to compare which complex will most effectively increase the anti-inflammatory activity of C. cibarius, inorganic and organic compounds were used. Both zinc salts were used in such quantities that the calculated additive amount of zinc into the culture media was the same. Control cultures were represented by in vitro cultures on Oddoux medium grown without the supplementation of zinc compounds. In addition, we studied which source of zinc is best for enhancing anti-inflammatory properties in A549 (Human Lung Epithelial Carcinoma, ATCC) cell models activated with lipopolysaccharide (LPS) to induce inflammation. Results of the study showed the important role of zinc during inflammation in the lung epithelial cells. Cantharellus cibarius in vitro cultures with high ability to accumulate zinc enabled the precise application of zinc compounds at a known concentration that may influence their immuno-modulatory properties.
Association between PM10 air pollution and birth weight after full-term pregnancy in Krakow city 1995–2009 – trimester specificity
(http://www.aaem.pl/, 2015) Merklinger-Gruchała, Anna; Kapiszewska, Maria
Introduction and objective. The results of epidemiological studies indicate that the higher maternal exposure to air pollution, especially with particulate matter during pregnancy, the lower the infant’s birth weight. The aim of this study was to estimate entire pregnancy and trimester-specific exposure of pregnant women in the city of Krakow, southern Poland, to fine particulate matter [≤10 μg (PM10)], and to assess its effect on the birth weight of boys and girls separately. Material and methods. The study group consisted of 85,000 singleton, live, full-term births in Krakow city during a 15-year period (data from the birth registry). The mean concentrations of the pollutant for each month of gestation were estimated using continuous municipal monitoring data. Results. Multiple linear regression analyses indicated that the mean PM10 concentration during entire pregnancy was inversely associated with birth weight in girls and the group of boys and girls combined, after adjusting for maternal age, gestational age and year of birth; in boys the relationship was not statistically significant. Maternal exposure to PM10 during the first trimester was negatively associated with birth weight separately in girls and boys, and the group of boys and girls combined. However, the PM10 exposure during the second and third trimester of pregnancy was not associated with birth weight. Conclusions. PM10 air pollution at levels currently encountered in Krakow city adversely affect infant birth weight; however, the effect seems to be very small. The influence of particulate air pollution on foetal growth in early gestation is one of several possible explanations for the results, but further research is needed to establish possible biological mechanisms explaining the observed relationship.
Changes in morphological and cytological properties of blood during physical exercise in water at 4oC and 25oC
(Wydawnictwo Akademii Wychowania Fizycznego w Krakowie, 2011) Teległów, Aneta; Bilski, Jan; Dąbrowski, Zbigniew; Marchewka, Anna; Jaśkiewicz, Jerzy; Głodzik, Jacek; Kępińska, Magdalena; Lizak, Dorota
Objective: The aim of this study was to determine the effect of a single swimming exercise till exhaustion, in water on the morphological and cytological blood parameters in laboratory rats. Methods: The experiment involved 60 male rats from the Wistar strain, aged 8 weeks and 36 weeks. The animals were separated into 6 groups: 3 groups (I, II, III) of 8-week old animals, and 3 groups (IV, V, VI) of 36-week old animals. The rats in the study groups i.e. II, III, V, and VI were made to swim till exhaustion in water at 4ºC and at 25°C. After the experiment blood samples were collected from each rat and hematological and cytological determinations were completed for each sample. Results: Compared with the control group, in the rats from group II (8-week old, swimming in water at 4ºC) a significant increase was noted in the RBC count, Hb, Ht, and MCHC, and MCH indices, whereas in the rats from group V (36-week old, swimming in water at 4ºC) increases were noted in the MCHC and MCH indices (again when compared with the control group). In the rats from group III (8-week old, swimming in water at 25ºC), compared with the control group, significant increases were noted in the Hb and Ht parameters, as well as in the MCHC, and MCH indices, whereas in the group VI rats (36-week old swimming at 25ºC) – the increase was noted in the MCHC index. No alterations were found in the reticulocyte count, and in poikilocytes during exercise in water at low temperatures in either the 8-week or 36-week old rats. Conclusions: The increases in the majority of blood parameters, testifies to the dehydration of the body during physical exercise which in turn affects the microcirculation function. The lack of alterations in the reticulocyte count in the peripheral blood may, in turn, testify to the ineffectiveness of low temperature during exercise upon the function of the bone marrow.
Clinical review of physical therapy intervention for ataxia
(Radomska Szkoła Wyższa, 2013) Grygus, Igor; Romanyshyn, Mykola
In the article the clinical activity of a physical therapist for patients with ataxia. Analyzed the causes of ataxia, physical examination of patient and rehabilitation interventions in this pathology. Ataxia – (from the Greek α- [means denying] and τάξις order) means a violation of the coordination of voluntary movement, is a neurological symptom. Ataxia is a non-specific clinical manifestation, which indicates that the dysfunction of the nervous system, namely the ability to co-ordinate voluntary motions (for example, cerebellum). Codes of the International classification of functions, disability and health (ICF): b750 (Motor reflex functions), b755 (Involuntary movement reaction functions), b760 (Control of voluntary movement functions), b765 (Involuntary movement functions), b770 (Gait pattern functions). Various means of physical therapy efficiency are confirmed by international surveys of scientific and evidence-based practice, namely: approaches to improve proprioceptive, measures to improve balance, vestibular exercises, approaches to minimized limb ataxia and the use of supportive aids. Separately considered rehabilitative interventions to improve gait in patients with ataxia. Conclusion. The on top of mentioned elements of the physical therapy intervention to help the physical therapist to reduce signs of ataxia and minimize the limited opportunities, which arises as a result of this dysfunction.
Composition and Biological Properties of Agaricus bisporus Fruiting Bodies – a Review
(http://journal.pan.olsztyn.pl, 2017) Muszyńska, Bożena; Kała, Katarzyna; Rojowski, Jacek; Grzywacz, Agata; Opoka, Włodzimierz
White Agaricus bisporus is both the most popular and the most commonly eaten edible mushroom species in the world. It is popular not only because of its taste, but also due to its high level of nutrients: dietary fiber (chitin), essential, semi-essential amino acids, unsaturated fatty acids including linoleic and linolenic acids, easily digestible proteins, sterols, phenolic and indole compounds, and vitamins − especially provitamin D2 and B1, B2, B6, B7, and C. Fruiting bodies of A. bisporus have antioxidant, antibacterial, anti-inflammatory, antitumor, and immunomodulatory activity. The presence of antioxidant ergothioneine (which also displays the antimutagenic, chemo- and radioprotective activity) is also noteworthy. A. bisporus also contains derivatives of benzoquinone, a substance which belongs to the group of antibiotics. Studies of tyrosinase isolated from this species show its very high similarity to human tyrosinase. This points directly to the fact that this species could be a rich source of tyrosinase used for medicinal and cosmetics purposes. A. bisporus is also a rich source of selenium, zinc and other elements such as magnesium, copper, iron, potassium, sodium, calcium, phosphorus, sulfur or manganese. In conclusion, the presence of these compounds and elements with biological activity in fruiting bodies of A. bisporus confirms their nutraceutical and medicinal properties.
Dawstwo i transplantacje narządów w opinii studentów pielęgniarstwa studiów uzupełniających pomostowych
(Wydawnictwo Czelej, 2012) Romanowska, Urszula; Lizak, Dorota; Jaśkiewicz, Jerzy; Lipińska, Maria
Transplantacje są uznaną metodą terapeutyczną i szansą na powrót do zdrowia dla wielu chorych. Dla transplantologii ważne są uregulowania prawne, które umożliwiają pobranie narządów do przeszczepu od osób, po ich śmierci. W Polsce obowiązuje zasada zgody domniemanej na pobranie narządów lub tkanek do transplantacji Zgodnie z prawem, za moment śmierci przyjmuje się orzeczenie śmierci mózgu, jako rzeczywistej śmierci człowieka. Pomimo, że transplantacja, jako metoda leczenia zyskała powszechną aprobatę, wymienione uregulowania prawne nie są przez wszystkich akceptowane, bowiem spotykają się zarówno z krytyką jak i sprzeciwem. Cel pracy. Celem badań było poznanie opinii i postaw studentów pielęgniarstwa studiów uzupełniających pomostowych, wobec dawstwa i transplantacji narządów pobranych od dawców żywych, spokrewnionych jak i osób uznanych za zmarłe w wyniku orzeczenia u nich śmierci mózgu. Metoda i materiał. W badaniach zastosowano metodę sondażu diagnostycznego, jako technikę wykorzystano kwestionariusz ankiety własnej konstrukcji. Badaniami objęto grupę 100 osób, pielęgniarek/pielęgniarzy, studentów studiów pomostowych, kierunku pielęgniarstwo, pracujących w zakładach opieki zdrowotnej na terenie Małopolski. Badania przeprowadzono w maju 2012 roku.
High tea consumption diminishes salivary 17beta-estradiol concetration in Polish women
(Cambridge University Press, 2006) Kapiszewska, Maria; Miśkiewicz, Małgorzata; Ellison, Peter T.; Thune, Inger; Jasieńska, Grażyna
We hypothesized that among reproductive-age women consuming large quantities of tea, the production of estradiol would be suppressed. It has been shown that catechins and theaflavines, the major constituents of tea, inhibit aromatase, an enzyme which catalyses the conversion of androgens to estrogens. Our study included Polish women living in urban (N=61) and rural (N=48) areas. Women collected daily saliva samples for one complete menstrual cycle and filled out dietary questionnaires. Saliva samples were analyzed by radioimmunoassay for concentration of 17-β estradiol (E2). Women with high (above the median) average daily consumption of black tea had reduced levels of salivary E2, in comparison with women who drank less black tea (below median). This effect was observed within the whole study group, as well as separately within urban (p = 0.0006) and rural (p = 0.013) groups. High intake of the sum of subclasses of tea catechins and epigallocatechin gallate, assessed using the USDA database [http://www.nal.usda.gov], was also associated with lower concentrations of E2 within all women (p = 0.01 and p = 0.0001, respectively) and within the urban group (p = 0.0001 and p = 0.004, respectively). Similar relationships were observed between the sum of subclasses of theaflavines and thearubigines and E2 levels for the whole group (p = 0.002) and for urban women (p = 0.02). Women with high consumption of tea had lower levels of E2 concentration throughout the entire menstrual cycle. These results may have implications for reducing hormone-related cancer risk by a relatively easy dietary intervention.
Improving physical performance in children with congenital clubfoot
(Medical Project Sp. z o.o., 2013) Mykhaylova, Nataliya; Grygus, Igor
Introduction. Pre-school period is one of the most crucial periods of human life in the formation of physical health and cultural skills to ensure the improvement, strengthening and preserving the futurę. Materials and ntethods. The study involved 68 pre-school children with congenital clubfoot: control group 1 (n = 34) and main group (n = 34) and healthy children (n = 34), who are the control group 2. At the beginning of the study the average age of children was 4-5 years. Children of the main group were constantly engaged in physical rehabilitation under the developed program. Participants of the control group were massaged and had a medical gymnastics twice a year. Results. The study improved physical performance in the main group: high at 14,71%, good in 52,94%, 32,35% in average. There was no significant increase in physical performance in the control groups. In the control group (number 2) good physical performance in the beginning of the study was 32,35% and it increased to 41,18% at the end of the study. In the control group (number 1) a good physical performance was at the beginning of 26,47%, and went up to 29,41%. Minor improvement of physical performance in children of control groups may have occurred even by reducing heart rate at rest. Conclusion. Average physical performance in the main group at the end of the study was 5,76±0,28 (p<0,05), corresponding to a good level of physical performance and demonstrates the effectiveness of the use of physical rehabilitation.
Moulding of professional and personal features of a character of future specialists on health
(2015) Grygus, Igor; Prusik, Krzysztof
The following article is studding and considering the results of the research work on the subject matter: personal example on the part of specialists on health in their activities in institutions of physical rehabilitation as well as their acquiring both physical and personal features of a character by the virtue of traditional Vedic (ancient Indian) knowledge such as Ayurveda and BhagavataPurana, which in turn contain some practical recommendations pertaining to support of health and development of consciousness on the basis of profound unity both of spiritual, psychological as well as physical state of a person.
Optymizing the level of physical health of students by type of autonomic nervous system
(Radomska Szkoła Wyższa, 2013) Grygus, Igor; Kuczer, Tetyana
We analyzed changes in the physical health of students of the Faculty of Physical Education under the influence of physical training by type of autonomic nervous system. In the study, 87 students attended the first and second year of study. The basis of the impact was the principle of individualized physical activity, regularity and gradualness. It was found that by including the autonomic nervous edge-type system, a much higher level of physical health indicators at the end of the study were the students' main group, in which the overall assessment of the level of physical health above average level reached in principle at the expense of improving the life, strength and index Robinson.
Polepszenie poziomu fizycznego zdrowia studentów przy pomocy zaproponowanych ćwiczeń ruchowych z uwzględnieniem typu autonomicznego nerwowego systemu
(Radomska Szkoła Wyższa, 2013) Grygus, Igor; Prusik, Krzysztof; Prusik, Katarzyna
Level of physical education in high school is not conducive to the effective reduction of the deficit of motive activity of students, which is one of the reasons various deviations in their health. The health of young people is essential and defining moment of well-being of society and its progressive development. The basic principle of the impact physical activity core group of students with different types of autonomic nervous system was the principle of individualization of physical activity, not dropping the weights regularity and consistency. The load volume was optimal, at the level of preparedness that much depended on the type of dominance of the autonomic nervous system. All students conducted a rapid assessment of the overall level of physical health by Apanasenko G.L. at the beginning and end of the study. With the prevalence of type counting of the autonomic nervous system, significantly higher levels of physical health were found among students at the end of the study the main group in which the overall assessment of physical health reached a level above the average.
Promocja zdrowia - realizm czy utopia?
(Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, 2015) Lizak, Dorota; Seń, Mariola
Dziedziną, która w ciągu ostatnich lat osiągnęła znaczny stopień popularności w skali globalnej jest promocja zdrowia. Wynika to nie tylko z jej historii (choć stosunkowo krótkiej) czy dorobku, ale działań podejmowanych na jej płaszczyźnie i niejednokrotnie bardzo dobrych efektów tych działań. Współczesne trendy zdrowotne jak i statystyki dotyczące zachorowalności czy umieralności wskazują na konieczność realizowania zadań z zakresu promocji zdrowia, bowiem tendencje te wynikają w dużej mierze z niewłaściwego czy też nieracjonalnego stylu życia jednostek, a często również z deficytu wiedzy. Aby jednak uczynić go bardziej racjonalnym, potrzebna jest wiedza upowszechniana przez profesjonalistów, tj. osoby merytorycznie przygotowane do jej krzewienia. Promocja zdrowia nie jest jedynie ideą, która ma zapełniać niszę w naukach o zdrowiu, ale przez lata wdrażania i kultywowania pewnych zasad i przekonań, wynikających z doświadczeń i obserwacji, okazuje się być inicjatywą przynoszącą wymierne korzyści. Przegląd rozpowszechnionych i coraz bardziej popularyzowanych zagadnień zdrowotnych w mediach pozwala na stwierdzenie, że zdrowie i jego umacnianie staje się tematem modnym. W związku z powyższym, aby móc istnieć we współczesnych realiach należy mieć świadomość procesów i stanów rzeczy jakie dzieją się wokół jednostki. Dlatego też promocja zdrowia stanowi integralną część zdrowia publicznego, zaś człowiek, będąc częścią społeczeństwa, partycypuje własnym zdrowiem w zdrowiu zbiorowości, stanowiąc jej podmiot składowy. Przyczyniając się jednak do jego budowania, powinien posiadać elementarną wiedzę o tej niematerialnej wartości.
Przegląd antropometrycznych mierników otłuszczenia ciała stosowanych w diagnozowaniu otyłości
(Oficyna Wydawnicza MA, 2016-06) Lizak, Dorota; Budzowski, Artur; Seń, Mariola; Czarny, Wojciech
Tendencje zdrowotne dotyczące zwiększania masy i wymiarów ciała wśród dzieci, młodzieży, a także osób dorosłych w Polsce nie są optymistyczne. Polska należy do krajów, w których to zjawisko, a właściwie problem zdrowotny zaznacza się w sposób szczególny, tj. ma charakter wzrostowy. O ile BMI (Body Mass Index, wskaźnik Queteleta II) uważany był do tej pory za adekwatny (optymalny) wskaźnik antropometryczny obrazujący stosunek masy ciała do wysokości ciała, tym samym na jego podstawie dokonywana była ocena prawidłowości bądź nieprawidłowości budowy lub funkcjonowania organizmu, tak w ostatnich latach został opracowany nowy miernik odnoszący się do procentowej zawartości tkanki tłuszczowej w ciele, a mianowicie BAI (Body Adiposity Index), czyli wskaźnik otłuszczenia ciała. Różnice w interpretowaniu tych samych cech somatycznych u różnych osób za pomocą obydwu wskaźników pozwalają wnioskować, iż BMI nie jest najbardziej rzetelnym miernikiem obrazującym ilość tkanki tłuszczowej w organizmie. Odnosi się bowiem do oceny masy ciała, a nie bezpośrednio do zawartości tkanki tłuszczowej. Rozpatrując wskaźniki BMI i BAI w kontekście zapobiegania chorobom sercowo-naczyniowym na podstawie dostępnych w piśmiennictwie wyników badań można stwierdzić, że obydwa wskaźniki w zróżnicowanym stopniu korelują ze zwiększonym ryzykiem występowania tych chorób. Wskaźnik BAI umożliwia szybsze i bardziej precyzyjne diagnozowanie otyłości i ryzyka chorób z nią związanych, jednak wymaga dalszej walidacji. Pomimo tego, zalety BAI predestynują go do włączenia do zestawu stosowanych powszechnie wskaźników antropometrycznych. W niniejszej pracy została poddana ocenie wiarygodność porównywanych wskaźników w świetle dotychczas uzyskanych wyników badań naukowych.
Resolvin D2 plays a protective role in RAW 264.7 Cells treated with polycyclic aromatic hydrocarbons
(Polish Academy of Sciences – Cracow Branch, 2015) Gdula-Argasińska, Joanna; Woźniakiewicz, Aneta; Woźniakiewicz, Michał; Lipkowska, Anna; Olbert, Magdalena; Grzywacz, Agata; Sałat, Kinga; Podkowa, Adrian; Librowski, Tadeusz
Eicosanoids are signaling molecules that control the immune processes and might have effects on inflammatory diseases. The aim of our study was to evaluate the effect of added resolvin D2 (RvD2), after treatment with polycyclic aromatic hydrocarbons (PAHs), on RAW 264.7 cells by using a UHPLC/MS-TOF method for the quantification of eicosanoids: 8-iPGF3α, PGF3α, 8-isoPGF2α, PGF2α and 5-iPF2α as well as cyclooxygenase 2 (COX-2), prostaglandin E synthase (cPGES) and prostaglandin F2α (FP) receptor protein expression by Western blot. The levels of PGF3α, PGF2α 8-iPGF3α 8-isoPGF2α and 5-iPF2α were decreased in RAW 264.7 cells after the exposure to PAHs and treatment with RvD2. It was observed that COX-2, cPGES and FP-receptor expression was decreased after co-treatment of the cells with PAHs and RvD2. Our findings suggest that RvD2 has anti-oxidant, anti-inflammatory and pro-resolving properties that may contribute significantly to alleviation of the harmful effects caused by PAHs in macrophages. Moreover, these results suggest that a diet rich in n-3 fatty acids might be helpful in resolving the inflammation and mitigating the effects of environmental stress in macrophages.
Short interpregnancy interval and low birth weight: a role of parity
(Wiley, 2015-03) Merklinger-Gruchała, Anna; Jasienska, Grazyna; Kapiszewska, Maria
Objectives: Short interpregnancy intervals (IPI) and high parity may be synergistically associated with the risk of unfavorable pregnancy outcomes. This study tests if the effect of short IPI on the odds ratio for low birth weight (LBW, <2,500 g) differs across parity status. Methods: The study was carried out on the birth registry sample of almost 40,000 singleton, live-born infants who were delivered between the years 1995 and 2009 to multiparous mothers whose residence at the time of infant’s birth was the city of Krakow. Multiple logistic regression analyses were used for testing the effect of IPI on the odds ratio (OR) for LBW, after controlling for employment, educational and marital status, parity, sex of the child, maternal and gestational age. Stratified analyses (according to parity) and tests for interaction were performed. Results: Very short IPI (0–5 months) was associated with an increased OR for LBW, but only among high parity mothers with three or more births (OR = 2.64; 95% CI 1.45–4.80). The test for interaction between very short IPI and parity on the OR for LBW was statistically significant after adjustment for multiple comparisons (P = 0.04). Among low parity mothers (two births) no statistically significant associations were found between IPI and LBW after standardization. Conclusion: Parity may modify the association between short birth spacing and LBW. Women with very short IPI and high parity may have a higher risk of having LBW infants than those with very short IPI but low parity.
The principles of sanitary and epidemiological restrictions of artificial ultraviolet rays emanation in sun parlors
(Radomska Szkoła Wyższa, 2013) Akymenko, V.Y.; Yarygin, A.V.; Khodakovskaya, V.A.; Avramenko, L.M.; Grygus, Igor
Was conducted analytical overview of existing principles regulating the usage of artificial ultraviolet emission in solariums in Russian Federation, Republic of Belarus, and also of the integrating recommendations of the WHO, in comparison with the results of our own research. This allows to define key directions of scientific-research activities in the sphere of evaluating the influence of this harmful factor on the organism of solariums visitors. Was proved the necessity of developing methodological recommendations and sanitaryepidemiological requirements to the operation of solariums.
The problem of postural defects in children and adolescents and the role of school teachers and counselors in their prevention
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2014) Lizak, Dorota; Czarny, Wojciech; Niewczas, Marta
Wady postawy ciała zarówno u dzieci jak i młodzieży stanowią istotny problem zdrowotny, a zarazem wyzwanie dla podstawowej opieki zdrowotnej oraz środowiska nauczania i wychowania. Kluczową rolę w diagnozowaniu wad postawy ciała odgrywa pielęgniarka szkolna. Celem opracowania jest ocena częstości występowania wad postawy u dzieci i młodzieży oraz ukazanie roli pracowników środowiska nauczania i wychowania w ich zapobieganiu. Wyniki badań przesiewowych uczniów wskazują na liczne nieprawidłowości w zakresie układu kostno-stawowego, a tym samym częste występowanie wad postawy ciała. Wdrożenie i realizacja gimnastyki korekcyjnej wydaje się być zatem kluczowym działaniem kompensująco-naprawczym, umożliwiającym zahamowanie progresji zmian. Istnieją jednak pewne utrudnienia, zmniejszające szansę na odpowiednio wczesne wdrożenie takich działań. Brak bilansu zdrowia uczniów w ostatniej klasie szkoły gimnazjalnej opóźnia wykrycie wady i może skutkować jej utrwaleniem. Może to prowadzić do deformacji, a w efekcie kosztów związanych z późniejszym leczeniem i rehabilitacją. Dokonywany w tym czasie przez ucznia wybór szkoły ponadgimnazjalnej w dużej mierze rzutuje na przyszłość młodego człowieka, bowiem występujące wady stanowią przeciwwskazanie do wykonywania niektórych zawodów, o czym młody człowiek dowiaduje się już po podjęciu decyzji o wyborze szkoły.
The role of zinc in the pathogenesis and treatment of central nervous system (CNS) diseases. implications of zinc homeostasis for proper cns function
(Polish Pharmaceutical Society, 2014) Tyszka-Czochara, Małgorzata; Grzywacz, Agata; Gdula-Argasińska, Joanna; Librowski, Tadeusz; Wiliński, Bogdan; Opoka, Włodzimierz
Zinc, the essential trace element, is known to play multiple biological functions in human organism. This metal is a component of many structural as well as regulatory and catalytic proteins. The precise regulation of zinc homeostasis is essential for central nervous system and for the whole organism. Zinc plays a significant role in the brain development and in the proper brain function at every stage of life. This article is a review of knowledge about the role of zinc in central nervous system (CNS) function. The influence of this biometal on etiopathogenesis, prevention and treatment of selected brain diseases and disorders was discussed. Zinc imbalance can result not only from insufficient dietary intake, but also from impaired activity of zinc transport proteins and zinc dependent regulation of metabolic pathways. It is known that some neurodegenerative processes are connected with zinc dyshomeostasis and it may influence the state of Alzheimerís disease, depression and ageing-connected loss of cognitive function. The exact role of zinc and zinc-binding proteins in CNS pathogenesis processes is being under intensive investigation. The appropriate zinc supplementation in brain diseases may help in the prevention as well as in the proper treatment of several brain dysfunctions.
Wpływ ruchowej aktywności na stan zdrowia studentów
(Radomska Szkoła Wyższa, 2013) Grygus, Igor; Mykhaylova, Nataliya
Purpose – to improve the organizational and methodological foundations of physical education for the improvement of high school students in training. The study involved 152 students of the second year of the International Economics and Humanities University named after Stepan Demyanchuk. Students were divided into a control (n = 76) and primary (n = 76) groups, which were similar in age and physical development. At the end of the study, through the application of the proposed technique improvement in students the core group, was able to restore the function of the respiratory and cardiovascular systems to the possibilities of healthy untrained people. A similar increase in the functionality of the core group of students registered with the definition of the index Skibinski – held a combined evaluation of functions of the respiratory and cardiovascular systems of students and determine its growth with satisfactory to good level.
Wpływ zaproponowanej metodyki wychowania fizycznego na stan funkcjonalny studentów
(Radomska Szkoła Wyższa, 2013) Grygus, Igor; Jewtuch, Mykola
W artykule przeanalizowano wpływ zaproponowanej metodyki wychowania fizycznego dla uzdrowienia studentów uczelni wyższej w trakcie ich studiów. Dzięki stosowaniu zaproponowanej metodyki wychowania fizycznego dla uzdrowienia studentów udało się wiarygodnie zwiększyć adaptację i polepszyć możliwość wznowienia stanu funkcjonalnego organizmu po obciążeniu, a odpowiednio i stan zdrowia studentów głównej grupy.

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